Article
Does the lipR gene of tubercle bacilli have a role in tuberculosis transmission and pathogenesis?
Tuberculosis (Edinburgh, Scotland) - 1 Mar 2009
Sheline Katherine D, France Anne M, Talarico Sarah, Foxman Betsy, Zhang Lixin, Marrs Carl F, Bates Joseph H, Cave M Donald, Yang Zhenhua
Abstract excerpt
Mycobacterium tuberculosis lipases, a diverse class of enzymes involved in lipid metabolism, may have an important role in tuberculosis (TB) pathogenesis. We explored the association of large sequence polymorphism (LSP) in one of the M. tuberculosis lipase-encoding genes, lipR (Rv3084), with patient characteristics using a population-based sample of clinical isolates to elucidate the potential role of lipR in TB...
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