Article
Identification of an IS6110 insertion site in plcD, the unique phospholipase C gene of Mycobacterium bovis.
Journal of medical microbiology - 1 Apr 2006
Viana-Niero Cristina, Rodriguez Cesar Alejandro Rosales, Bigi Fabiana, Zanini Marcos Santos, Ferreira-Neto José Soares, Cataldi Angel, Leão Sylvia Cardoso
Abstract excerpt
The IS6110 repetitive element is present in multiple copies in most Mycobacterium tuberculosis complex bacteria, except for Mycobacterium bovis strains, which usually contain a single copy of IS6110 located on a 1.9 kb PvuII fragment of the direct repeat region. IS6110 transposition can disrupt coding regions and is a major force of genomic variation. In a previous work it was demonstrated that phospholipase C...
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