Article
Population-based study of deletions in five different genomic regions of Mycobacterium tuberculosis and possible clinical relevance of the deletions.
Journal of clinical microbiology - 1 Nov 2006
Kong Y, Cave M D, Zhang L, Foxman B, Marrs C F, Bates J H, Yang Z H
Abstract excerpt
Regions of difference (RDs) have been described in clinical isolates of Mycobacterium tuberculosis, but the potential epidemiological and clinical relevance of the genotypes of these RDs remains to be investigated. We screened a population-based sample of 648 isolates for the deletion of five RDs, designated RD105, RD181, RD142, RD150, and RD239, using microarray-based hybridization, PCR, and DNA sequencing and...
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