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Association of the MC4R V103I polymorphism with obesity: a Chinese case-control study and meta-analysis in 55,195 individuals.

Obesity (Silver Spring, Md.) - 1 Mar 2010

Wang Du, Ma Jun, Zhang Su, Hinney Anke, Hebebrand Johannes, Wang Yan, Wang Hai-Jun

Abstract excerpt

Recently, large-scaled studies suggested a negative association of the infrequent allele of the melanocortin-4 receptor (MC4R) V103I polymorphism with obesity. We conducted a Chinese case-control study, meta-analysis in East Asians and in all populations, in order to further assess the association between the V103I polymorphism and reduced body weight and to explore whether the association varies among different...

Topics

Asian People
Case-Control Studies
Child
China
Gene Frequency
Genetic Predisposition to Disease
Humans
Obesity
Odds Ratio
Phenotype
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptor, Melanocortin, Type 4

Risk Factors

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Identifiers

PMID: 19696756
DOI: 10.1038/oby.2009.268

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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