Article
Msx homeobox gene family and craniofacial development.
Cell research - 1 Dec 2003
Alappat Sylvia, Zhang Zun Yi, Chen Yi Ping
Abstract excerpt
Vertebrate Msx genes are unlinked, homeobox-containing genes that bear homology to the Drosophila muscle segment homeobox gene. These genes are expressed at multiple sites of tissue-tissue interactions during vertebrate embryonic development. Inductive interactions mediated by the Msx genes are essential for normal craniofacial, limb and ectodermal organ morphogenesis, and are also essential to survival in mice,...
Topics
- Animals
- Cleft Palate
- DNA-Binding Proteins
- Ectoderm
- Embryonic Induction
- Gene Expression Regulation, Developmental
- Genes, Homeobox
- Homeodomain Proteins
- Humans
- MSX1 Transcription Factor
- Maxillofacial Development
- Mesoderm
- Mice
- Mice, Knockout
- Models, Biological
- Morphogenesis
- Mutation
- Odontogenesis
