Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Determining Complete Chromosomal Haplotypes by mLinker.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2023

Sinha Sumit, Zhang Cheng-Zhong

Abstract excerpt

Haplotype ("haploid genotype") phase is the combination of genotypes at sites of genetic variation along a chromosome [1]. We previously demonstrated that the complete chromosomal haplotype of diploid human genomes can be determined using molecular linkage from Hi-C sequencing and linked-reads sequencing [2]. In this chapter, we present a step-by-step guide to perform this analysis using mLinker, a software...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Sequence Analysis, DNA
Share to Algorithms
Share to Chromosomes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome, Human

Share to Genotype

Share to Haplotypes

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 36335498
DOI: 10.1007/978-1-0716-2819-5_10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Determining Complete Chromosomal Haplotypes by mLinker.PMID 36335498Read ↗

Determination of complete chromosomal haplotypes by bulk DNA sequencingSemantic proximity Read ↗

GenomeLaser: fast and accurate haplotyping from pedigree genotypes.Semantic proximity Read ↗

Dense and accurate whole-chromosome haplotyping of individual genomes.Semantic proximity Read ↗

Haplotype Inference.Semantic proximity Read ↗

Haplotype inference.Semantic proximity Read ↗

Sequencing of isolated sperm cells for direct haplotyping of a human genome.Semantic proximity Read ↗

Computational Methods for Chromosome-Scale Haplotype ReconstructionSemantic proximity Read ↗

Chromosome-scale, haplotype-resolved assembly of human genomes.Semantic proximity Read ↗

Chromosomal haplotypes by genetic phasing of human families.Semantic proximity Read ↗

A fully phased accurate assembly of an individual human genomeSemantic proximity Read ↗

Whole-genome haplotyping using long reads and statistical methods.Semantic proximity Read ↗

Extending partial haplotypes to full genome haplotypes using chromosome conformation capture data.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.