A survey on haplotyping algorithms for tightly linked markers.

doi:10.1142/s0219720008003369

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Article

A survey on haplotyping algorithms for tightly linked markers.

Journal of bioinformatics and computational biology - 1 Feb 2008

Li Jing, Jiang Tao

Abstract excerpt

Two grand challenges in the postgenomic era are to develop a detailed understanding of heritable variation in the human genome, and to develop robust strategies for identifying the genetic contribution to diseases and drug responses. Haplotypes of single nucleotide polymorphisms (SNPs) have been...

Topics

Algorithms
Base Sequence
Chromosome Mapping
DNA Mutational Analysis
Genetic Markers
Haplotypes
Humans
Linkage Disequilibrium
Molecular Sequence Data
Polymorphism, Single Nucleotide
Sequence Analysis, DNA

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