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Article

The LPL/ADAM29 expression ratio is a novel prognosis indicator in chronic lymphocytic leukemia.

Blood - 15 Jul 2005

Oppezzo Pablo, Vasconcelos Yuri, Settegrana Catherine, Jeannel Dominique, Vuillier Françoise, Legarff-Tavernier Magali, Kimura Eliza Yuriko, Bechet Stéphane, Dumas Gérard, Brissard Martine, Merle-Béral Hélène, Yamamoto Mihoko, Dighiero Guillaume, Davi Frédéric

Abstract excerpt

Although the zeta-associated protein of 70 kDa (ZAP-70) is overexpressed in patients with chronic lymphocytic leukemia (CLL) displaying unmutated IGVH genes and poor prognosis, a previous microarray study from our group identified overexpression of LPL and ADAM29 genes among unmutated and mutated CLL, respectively. To assess the prognostic value of these genes, we quantified their expression by real-time...

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Topics

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Share to ADAM Proteins
Share to Genes, Immunoglobulin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin Heavy Chains

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Lipoprotein Lipase

Share to Metalloendopeptidases

Share to Protein-Tyrosine Kinases

Share to ZAP-70 Protein-Tyrosine Kinase

Source

Identifiers

PMID: 15802535
DOI: 10.1182/blood-2004-08-3344

Genes

ADAM29
LPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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