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Article

LPL gene expression is associated with poor prognosis in CLL and closely related to NOTCH1 mutations.

European journal of haematology - 1 Aug 2016

Kristensen Louise, Kristensen Thomas, Abildgaard Niels, Royo Cristina, Frederiksen Mikael, Mourits-Andersen Torben, Campo Elias, Møller Michael Boe

Abstract excerpt

INTRODUCTION: Chronic lymphocytic leukemia is a heterogeneous yet incurable disease. Whole-genome and whole-exome sequencing studies have revealed recurrently occurring somatic mutations in some genes. Several other prognostic markers have previously been tested for their prognostic value in CLL. LPL is among these markers. AIM: To evaluate LPL gene expression together with the well-established prognostic markers...

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Share to Antineoplastic Combined Chemotherapy Protocols
Share to Gene Expression Regulation, Leukemic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin Heavy Chains

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Lipoprotein Lipase

Share to Proportional Hazards Models

Share to Receptor, Notch1

Share to ZAP-70 Protein-Tyrosine Kinase

Source

Identifiers

PMID: 26558352
DOI: 10.1111/ejh.12700

Genes

LPL
NOTCH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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