Article
IGHV gene mutational status and LPL/ADAM29 gene expression as clinical outcome predictors in CLL patients in remission following treatment with oral fludarabine plus cyclophosphamide.
Annals of hematology - 1 Dec 2009
Maloum Karim, Settegrana Catherine, Chapiro Elise, Cazin Bruno, Leprêtre Stéphane, Delmer Alain, Leporrier Michel, Dreyfus Brigitte, Tournilhac Olivier, Mahe Beatrice, Nguyen-Khac Florence, Lesty Claude, Davi Frederic, Merle-Béral Hélène
Abstract excerpt
Several prognostic factors can predict the rapid progression in chronic lymphocytic leukaemia (CLL), including IGHV mutational status, cytogenetic abnormalities and, more recently, LPL/ADAM29 expression. In contrast, few studies have been devoted to the influence of these factors on clinical outc...
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