Article
Genome-based pharmacogenetics and the pharmaceutical industry.
Nature reviews. Drug discovery - 1 Jul 2002
Roses Allen D
Abstract excerpt
Pharmacogenetic capabilities have changed markedly since The SNP Consortium made a dense single-nucleotide polymorphism (SNP) map freely available in 2001. For more than 40 years, pharmacokinetics and pharmacodynamics of drug-metabolizing molecules were the focus of practical applications. Today, it is possible to use SNP-mapping technologies to create a genetic profile of each individual that can be used to...
Topics
- Clinical Trials as Topic
- Dideoxynucleosides
- Drug Industry
- Genetic Predisposition to Disease
- Genome
- Humans
- Pharmacogenetics
- Polymorphism, Single Nucleotide
- Proteome
