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Article

Domain interactions of the mannose 6-phosphate/insulin-like growth factor II receptor.

The Journal of biological chemistry - 3 Jun 2005

Kreiling Jodi L, Byrd James C, MacDonald Richard G

Abstract excerpt

The mannose 6-phosphate/insulin-like growth factor II receptor (M6P/IGF2R) forms oligomeric structures important for optimal function in binding and internalization of Man-6-P-bearing extracellular ligands as well as lysosomal biogenesis and growth regulation. However, neither the mechanism of inter-receptor interaction nor the dimerization domain has yet been identified. We hypothesized that areas near the...

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PMID: 15799974
DOI: 10.1074/jbc.M412971200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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