Article
A family of K+ channel ancillary subunits regulate taste sensitivity in Caenorhabditis elegans.
The Journal of biological chemistry - 10 Jun 2005
Park Ki Ho, Hernandez Leonardo, Cai Shi-Qing, Wang Yi, Sesti Federico
Abstract excerpt
We have identified a family of ancillary subunits of K(+) channels in Caenorhabditis elegans. MPS-1 and its related members MPS-2, MPS-3, and MPS-4 are detected in the nervous system of the nematode. Electrophysiological analysis in ASE neurons and mammalian cells and epigenetic inactivation by double-stranded RNA interference (RNAi) in vivo show that each MPS can associate with and functionally endow the...
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