Article
A potassium channel-MiRP complex controls neurosensory function in Caenorhabditis elegans.
The Journal of biological chemistry - 4 Apr 2003
Bianchi Laura, Kwok Suk-Mei, Driscoll Monica, Sesti Federico
Abstract excerpt
MinK-related peptides (MiRPs) are single transmembrane proteins that associate with mammalian voltage-gated K(+) subunits. Here we report the cloning and functional characterization of a MiRP beta-subunit, MPS-1, and of a voltage-gated pore-forming potassium subunit, KVS-1, from the nematode Caenorhabditis elegans. mps-1 is expressed in chemosensory and mechanosensory neurons and co-localizes with kvs-1 in a...
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