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Article

Decoding of polymodal sensory stimuli by postsynaptic glutamate receptors in C. elegans.

Neuron - 5 Dec 2002

Mellem Jerry E, Brockie Penelope J, Zheng Yi, Madsen David M, Maricq Andres V

Abstract excerpt

The C. elegans polymodal ASH sensory neurons detect mechanical, osmotic, and chemical stimuli and release glutamate to signal avoidance responses. To investigate the mechanisms of this polymodal signaling, we have characterized the role of postsynaptic glutamate receptors in mediating the response to these distinct stimuli. By studying the behavioral and electrophysiological properties of worms defective for...

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PMID: 12467596
DOI: 10.1016/s0896-6273(02)01088-7

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