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The mechanoreceptor DEG‐1 regulates cold tolerance in Caenorhabditis elegans

3 Feb 2020

Abstract excerpt

Abstract Caenorhabditis elegans mechanoreceptors located in ASG sensory neurons have been found to sense ambient temperature, which is a key trait for animal survival. Here, we show that experimental loss of xanthine dehydrogenase (XDH‐1) function in AIN and AVJ interneurons results in reduced cold tolerance and atypical neuronal response to changes in temperature. These interneurons connect with upstream neurons...

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PMID: 32009302
DOI: 10.15252/embr.201948671

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