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Article

Asymmetric distribution of EGFR receptor during mitosis generates diverse CNS progenitor cells.

Neuron - 24 Mar 2005

Sun Yu, Goderie Susan K, Temple Sally

Abstract excerpt

It has been debated whether asymmetric distribution of cell surface receptors during mitosis could generate asymmetric cell divisions by yielding daughters with different environmental responsiveness and, thus, different fates. We have found that in mouse embryonic forebrain ventricular and subventricular zones, the EGFR can distribute asymmetrically during mitosis in vivo and in vitro. This occurs during...

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Identifiers

PMID: 15797549
DOI: 10.1016/j.neuron.2005.01.045

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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