Article
Restricted perinatal retinal degeneration induces retina reshaping and correlated structural rearrangement of the retinotopic map.
Nature communications - 1 Jan 2013
Maiorano Nicola A, Hindges Robert
Abstract excerpt
The formation of the retinotopic map depends on the action of axon guidance molecules, activity-dependent mechanisms and axonal competition. However, little is known about the plasticity potential of the system and the effects on the remodelling of retinocollicular connections upon retinal insults. Here we create a mouse model in which retinal ganglion cells that project to anterior and posterior superior...
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