Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Allelic loss at 10q26 in osteosarcoma in the region of the BUB3 and FGFR2 genes.

Cancer genetics and cytogenetics - 15 Apr 2005

Mendoza Susana, David Heldi, Gaylord Grace M, Miller Carl W

Abstract excerpt

Loss of heterozygosity at 10q26 was mapped using microsatellite markers in 20 osteosarcomas. A four-megabase region centered on marker D10S587 was affected by allelic loss in 60 percent of osteosarcomas. The most frequently lost marker was D10S1723. Around 15 known genes are found in this region. The gene immediately adjacent to D10S1723 encodes BUB3, an element of the spindle assembly mitotic checkpoint. Loss of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 10
Share to Introns
Share to Loss of Heterozygosity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Osteosarcoma

Share to Poly-ADP-Ribose Binding Proteins

Share to Receptor, Fibroblast Growth Factor, Type 2

Share to Receptor Protein-Tyrosine Kinases

Share to Receptors, Fibroblast Growth Factor

Source

Identifiers

PMID: 15796961
DOI: 10.1016/j.cancergencyto.2004.08.035

Genes

BUB3
FGFR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Allelic loss at 10q26 in osteosarcoma in the region of the BUB3 and FGFR2 genes.PMID 15796961Read ↗

Genomic instability at the BUB1 locus in colorectal cancer, but not in non-small cell lung cancer.Semantic proximity Read ↗

Germline Mutations in the Spindle Assembly Checkpoint Genes BUB1 and BUB3 Are Risk Factors for Colorectal CancerSemantic proximity Read ↗

Prevalence of germline mutations in the spindle assembly checkpoint gene BUB1B in individuals with early-onset colorectal cancer.Semantic proximity Read ↗

Research progress of Bub3 gene in malignant tumorsSemantic proximity Read ↗

Four single-nucleotide polymorphisms in the human BUB1 gene.Semantic proximity Read ↗

Frequent loss of heterozygosity for markers on chromosome arm 10q in chondrosarcomas.Semantic proximity Read ↗

Fine deletional mapping of chromosome 4q22-35 region in oral cancer.Semantic proximity Read ↗

Loss of heterozygosity of chromosome 10p in human gliomas.Semantic proximity Read ↗

A region of deletion on chromosome 22q13 is common to human breast and colorectal cancers.Semantic proximity Read ↗

Refinement of two chromosome 11q regions of loss of heterozygosity in ovarian cancer.Semantic proximity Read ↗

Loss of heterozygosity and microsatellite instability at the retinoblastoma locus in osteosarcomas.Semantic proximity Read ↗

Two novel tumor suppressor gene loci on chromosome 6q and 15q in human osteosarcoma identified through comparative study of allelic imbalances in mouse and man.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.