Article
The presence of tandem endothelial nitric oxide synthase gene polymorphisms identifying brain aneurysms more prone to rupture.
Journal of neurosurgery - 1 Mar 2005
Khurana Vini G, Meissner Irene, Sohni Youvraj R, Bamlet William R, McClelland Robyn L, Cunningham Julie M, Meyer Fredric B
Abstract excerpt
OBJECT: It is becoming apparent that the presence of certain genetic variations (polymorphisms) may increase the individual's susceptibility to cardiovascular diseases, even in the absence of a family history. We hypothesized that brain aneurysms more prone to rupture may be identified on the basis of an individual's genotype for endothelial nitric oxide synthase (eNOS), a critical vasomodulatory protein found to...
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