Article
Using endothelial nitric oxide synthase gene polymorphisms to identify intracranial aneurysms more prone to rupture in Japanese patients.
Journal of neurosurgery - 1 Nov 2006
Krischek Boris, Kasuya Hidetoshi, Akagawa Hiroyuki, Tajima Atsushi, Narita Akira, Onda Hideaki, Hori Tomokatsu, Inoue Ituro
Abstract excerpt
OBJECT: Recent investigators found that the presence of three tandem polymorphisms of the endothelial nitric oxide synthase (eNOS) gene-promoter single nucleotide polymorphism (SNP) T-786C, intron-4 27-bp variable number of tandem repeats, and the G894T SNP in exon 7-was indicative of intracranial aneurysms more prone to rupture in a Caucasian patient sample. In the present study, the authors sought to determine...
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