Article
[Intracranial aneurysms and their clinical and genetic behaviour].
Cirugia y cirujanos - 1 Jan 2000
García-Ortiz Liliana, Gutiérrez-Salinas José, Guerrero-Muñiz Salvador, Chima-Galán María del Carmen, Sánchez-Hernández Jonathan
Abstract excerpt
BACKGROUND: Intracranial aneurysms are abnormal dilations of the cerebral arteries of unknown origin. However, some genes have been linked to their formation, as in the case of NOS3 gene which encodes the endothelial nitric oxide synthase responsible for producing nitric oxide. Several polymorphisms in this gene, in association with a variable number tandem repeat located in intron 4 from eNOS4 gene, can...
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