Article
Update on evidence for a genetic predisposition to cerebral vasospasm.
Neurosurgical focus - 15 Sept 2006
Khurana Vini G, Fox Douglas J, Meissner Irene, Meyer Fredric B, Spetzler Robert F
Abstract excerpt
Considerable evidence links cerebral vasospasm to the decreased bioavailability of endothelial nitric oxide synthase (eNOS) after aneurysmal subarachnoid hemorrhage (SAH). In recent studies from the cardiology literature, researchers have suggested that a genetic predisposition to coronary vasospasm might develop as the result of a T-786C single nucleotide polymorphism (SNP) in the eNOS gene. The authors of this...
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