Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Therapeutic implications of polymorphisms in cytochromes and drug transporters].

Wiener medizinische Wochenschrift (1946) - 1 Feb 2005

Münster Eva, Ziegler Sophie, Brunner Martin

Abstract excerpt

There is great heterogeneity in the way individuals respond to drug therapy. Reasons for this variability include pathophysiological or environmental factors, drug interactions or genetic influences. Among those influences are polymorphisms in drug-metabolizing enzymes, such as Cytochrom-P-450 (CYP) 2D6, CYP2C9 or CYP2C19 or genetic variants in enzymes coding for drug transporters, such as P-Glycoprotein....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytochrome P-450 Enzyme System
Share to Drug-Related Side Effects and Adverse Reactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Therapy

Share to Genetic Testing

Share to Patient Selection

Share to Pharmaceutical Preparations

Share to Pharmacogenetics

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 15791777
DOI: 10.1007/s10354-004-0144-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Therapeutic implications of polymorphisms in cytochromes and drug transporters].PMID 15791777Read ↗

[Clinical relevance of drug metabolism polymorphisms].Semantic proximity Read ↗

[Xenobiotic-metabolizing polymorphic enzymes. An opportunity for individualized drug treatment].Semantic proximity Read ↗

Pharmacogenetics of drug metabolising enzymes: importance for personalised medicine.Semantic proximity Read ↗

Cytochrome P450 Enzyme System: Genetic Polymorphisms and Impact on Clinical PharmacologySemantic proximity Read ↗

[Genetic polymorphisms in drug-metabolizing enzymes].Semantic proximity Read ↗

[Genetic polymorphism of drug metabolizing enzymes].Semantic proximity Read ↗

Clinical Pharmacogenetics and Potential Application in Personalized MedicineSemantic proximity Read ↗

Pharmacogenetics of drug metabolizing enzymes and transporters: effects on pharmacokinetics and pharmacodynamics of anticancer agents.Semantic proximity Read ↗

[Clinical significance of some genetic polymorphisms of cytochrome P-450 subfamilies CYP2D, CYP2E and CYP3A--part II].Semantic proximity Read ↗

Polymorphism of human cytochrome P450 enzymes and its clinical impact.Semantic proximity Read ↗

[Clinical significance of some genetic polymorphisms of cytochrome P-450: family CYP1 and subfamilies CYP2A, CYP2B and CYP2C].Semantic proximity Read ↗

Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.