Article
Tumor necrosis factor-alpha promoter polymorphism in Mexican patients with Chagas' disease.
Immunology letters - 15 Apr 2005
Rodríguez-Pérez José Manuel, Cruz-Robles David, Hernández-Pacheco Guadalupe, Pérez-Hernández Nonanzit, Murguía Luis Enrique, Granados Julio, Reyes Pedro Antonio, Vargas-Alarcón Gilberto
Abstract excerpt
The aim of this study was to investigate whether the promoter's polymorphisms at the TNF alpha (TNF-alpha) gene were associated with the genetic susceptibility to Chagas' disease. We analyzed the TNF-alpha (positions -308, and -238) polymorphisms in a sample of 54 serologically positive chagasic individuals and in 169 healthy controls. The patients were divided according to clinical characteristics as...
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