Article
Tumor necrosis factor-alpha gene promoter -308G/A and -238G/A polymorphisms in Mexican patients with type 2 diabetes mellitus.
Disease markers - 1 Jan 2011
Guzmán-Flores Juan Manuel, Muñoz-Valle José Francisco, Sánchez-Corona José, Cobián José G, Medina-Carrillo Leopoldo, García-Zapién Alejandra G, Cruz-Quevedo Edhit G, Flores-Martínez Silvia Esperanza
Abstract excerpt
The association between some Tumor necrosis factor-alpha (TNF-α) promoter polymorphisms and Type 2 diabetes mellitus (T2DM) remains controversial. Ethnic differences may play a role in these conflicting results. The aim of this study was to investigate the association between -308G/A and -238G/A polymorphisms located in the promoter region of the TNF-α gene and T2DM in Mexican mestizo patients. Nine hundred four...
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