Article
Bayesian modelling of multivariate quantitative traits using seemingly unrelated regressions.
Genetic epidemiology - 1 May 2005
Verzilli Claudio J, Stallard Nigel, Whittaker John C
Abstract excerpt
We investigate a Bayesian approach to modelling the statistical association between markers at multiple loci and multivariate quantitative traits. In particular, we describe the use of Bayesian Seemingly Unrelated Regressions (SUR) whereby genotypes at the different loci are allowed to have non-simultaneous effects on the phenotypes considered with residuals from each regression assumed correlated. We present...
Topics
- Algorithms
- Anticholesteremic Agents
- Apolipoproteins E
- Atorvastatin
- Bayes Theorem
- Cholesterol
- Cholesterol, LDL
- Computer Simulation
- Genotype
- Heptanoic Acids
- Humans
- Models, Genetic
- Models, Statistical
- Multivariate Analysis
- Phenotype
- Polymorphism, Single Nucleotide
- Pyrroles
- Quantitative Trait Loci
