Article
Complex system approaches to genetic analysis Bayesian approaches.
Advances in genetics - 1 Jan 2010
Wilson Melanie A, Baurley James W, Thomas Duncan C, Conti David V
Abstract excerpt
Genetic epidemiology is increasingly focused on complex diseases involving multiple genes and environmental factors, often interacting in complex ways. Although standard frequentist methods still have a role in hypothesis generation and testing for discovery of novel main effects and interactions, Bayesian methods are particularly well suited to modeling the relationships in an integrated "systems biology"...
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