Article
[Cloning and sequencing HLA-A and -B genomic DNA and analyzing polymorphism in regulatory regions in Chinese Han individuals].
Yi chuan = Hereditas - 1 Jul 2010
Xu Yun-Ping, Deng Zhi-Hui, Zou Hong-Yan, Gao Su-Qing, Wang Da-Ming, He Liu-Mei, Wei Tian-Li
Abstract excerpt
In the present study, a high-resolute method for cloning and sequencing genomic full-length HLA-A and -B using 20 Chinese Han individuals was established. We detected 10 HLA-A allele sequences 4.2 kb in length and 6 HLA-B allele sequences 3.7 kb in length, and the sequences included all exons, all introns, 5'promoter, and 3'UTR of the two genes. All sixteen sequences have been submitted to GenBank and IMGT/HLA...
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