Article
Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPARgamma-2) gene is associated with greater insulin sensitivity and decreased risk of type 2 diabetes in an Iranian population.
Clinical chemistry and laboratory medicine - 1 Jan 2007
Meshkani Reza, Taghikhani Mohammad, Larijani Bagher, Bahrami Yadollah, Khatami Shohreh, Khoshbin Ehteram, Ghaemi Amir, Sadeghi Sedigheh, Mirkhani Fatemeh, Molapour Azam, Adeli Khosrow
Abstract excerpt
BACKGROUND: The Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPARgamma-2) gene has been variably associated with insulin resistance, obesity and type 2 diabetes in several populations. However, this association has not been studied in Iranian subjects and we hypothesized that this variation might be associated with insulin resistance, type 2 diabetes and related metabolic traits...
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