Article
A comprehensive review of uncommon EGFR mutations in patients with non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Dec 2017
Tu Hai-Yan, Ke E-E, Yang Jin-Ji, Sun Yue-Li, Yan Hong-Hong, Zheng Ming-Ying, Bai Xiao-Yan, Wang Zhen, Su Jian, Chen Zhi-Hong, Zhang Xu-Chao, Dong Zhong-Yi, Wu Si-Pei, Jiang Ben-Yuan, Chen Hua-Jun, Wang Bin-Chao, Xu Chong-Rui, Zhou Qing, Mei Ping, Luo Dong-Lan, Zhong Wen-Zhao, Yang Xue-Ning, Wu Yi-Long
Abstract excerpt
INTRODUCTION: Patients with non-small cell lung cancer (NSCLC) harboring uncommon epidermal growth factor receptor (EGFR) mutations are a heterogeneous group exhibiting differential responses to EGFR inhibitors. This retrospective study reviews the prevalence of uncommon EGFR mutations in a Chinese NSCLC cohort and the clinical characteristics and efficacy of EGFR tyrosine kinase inhibitors (TKIs) associated with...
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