Article
Resident Th1-like effector memory cells in pulmonary recall responses to Mycobacterium tuberculosis.
American journal of respiratory cell and molecular biology - 1 Jul 2005
Walrath Jessica, Zukowski Lynn, Krywiak Adriana, Silver Richard F
Abstract excerpt
We recently described a model of Th1 recall responses based on segmental antigen challenge with purified protein derivative of Mycobacterium tuberculosis (PPD). Bronchoscopic instillation of 0.5 tuberculin units of PPD resulted in localized lymphocytic inflammation in PPD-positive subjects only. Recruited lymphocytes were predominantly CD4+ and were enriched for cells capable of PPD-specific interferon...
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