Article
T-Cell Responses to CD1-Presented Lipid Antigens in Humans with <i>Mycobacterium tuberculosis</i> Infection
21 May 2003
Abstract excerpt
CD1-restricted presentation of lipid or glycolipid antigens derived from Mycobacterium tuberculosis has been demonstrated by in vitro experiments using cultured T-cell lines. In the present work, the frequency of T-cell responses to natural mycobacterial lipids was analyzed in ex vivo studies of peripheral blood lymphocytes from human patients with pulmonary tuberculosis, from asymptomatic individuals with known...
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