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Article

Extrusion of cells with inappropriate Dpp signaling from Drosophila wing disc epithelia.

Science (New York, N.Y.) - 18 Mar 2005

Shen Jie, Dahmann Christian

Abstract excerpt

Decapentaplegic (Dpp) is a signaling molecule that controls growth and patterning of the developing Drosophila wing. Mutant cells lacking Dpp signal transduction have been shown to activate c-Jun amino-terminal kinase (JNK)-dependent apoptosis and to be lost from the wing disc epithelium. These observations have led to the hypothesis that Dpp promotes cell survival by preventing apoptosis. Here, we show that in...

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Identifiers

PMID: 15774763
DOI: 10.1126/science.1104784

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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