Article
Local Cell Death Changes the Orientation of Cell Division in the Developing Drosophila Wing Imaginal Disc Without Using Fat or Dachsous as Orienting Signals.
PloS one - 1 Jan 2016
Kale Abhijit, Rimesso Gerard, Baker Nicholas E
Abstract excerpt
Drosophila imaginal disc cells exhibit preferred cell division orientations according to location within the disc. These orientations are altered if cell death occurs within the epithelium, such as is caused by cell competition or by genotypes affecting cell survival. Both normal cell division orientations, and their orientations after cell death, depend on the Fat-Dachsous pathway of planar cell polarity (PCP)....
Topics
- Animals
- Cadherins
- Cell Adhesion Molecules
- Cell Death
- Cell Division
- Cell Polarity
- Drosophila Proteins
- Drosophila melanogaster
- Genotype
- Imaginal Discs
- Signal Transduction
- Wings, Animal