Regulation of cellular responsiveness to inductive signals in the developing C. elegans nervous system.

doi:10.1038/350712a0

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Article

Regulation of cellular responsiveness to inductive signals in the developing C. elegans nervous system.

Nature - 25 Apr 1991

Waring D A, Kenyon C

Abstract excerpt

In Caenorhabditis elegans, cell-cell communication is required to form a simple pattern of sensory ray neurons and cuticular structures (alae). The C. elegans pal-1 gene initiates one developmental pathway (ray lineages) simply by blocking a cell-cell interaction that induces an alternative pathway. Here we show by mosaic analysis that pal-1+ acts by preventing specific cells from responding to inductive signals....

Topics

Amino Acid Sequence
Animals
Base Sequence
Caenorhabditis
Caenorhabditis elegans Proteins
Cell Communication
Genotype
Helminth Proteins
Homeodomain Proteins
Models, Biological
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mosaicism

Mutation

Nervous System

Nervous System Physiological Phenomena

Neurons

Phenotype

Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 2023634
DOI: 10.1038/350712a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2023634-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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