Article
Regulation of cellular responsiveness to inductive signals in the developing C. elegans nervous system.
Nature - 25 Apr 1991
Waring D A, Kenyon C
Abstract excerpt
In Caenorhabditis elegans, cell-cell communication is required to form a simple pattern of sensory ray neurons and cuticular structures (alae). The C. elegans pal-1 gene initiates one developmental pathway (ray lineages) simply by blocking a cell-cell interaction that induces an alternative pathway. Here we show by mosaic analysis that pal-1+ acts by preventing specific cells from responding to inductive signals....
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