Article
The SOX9 Transcription Factor in the Human Disc: Decreased Immunolocalization With Age and Disc Degeneration
1 Mar 2005
Abstract excerpt
In Brief Study Design. Human intervertebral disc anulus tissue was obtained in a prospective study of immunolocalization of SOX9, a protein that plays a role in chondrogenesis and Type II collagen expression. The Human Subjects Institutional Review Board approved experimental studies. Discs were obtained from surgical specimens and from control donors. Objectives. To determine whether SOX9 could be detected in...
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