Article
Lack of association of the CD14/C-159T polymorphism with susceptibility and serological activity parameters of rheumatoid arthritis.
Scandinavian journal of rheumatology - 1 Jan 2000
de la Fontaine L, Schwarz M, Plischke H, Kleindienst N, Gruber R
Abstract excerpt
OBJECTIVE: CD14, the monocyte receptor for lipopolysaccharides (LPS), is an important mediator of inflammatory processes. As the T-159C exchange in the promotor of the CD14 gene was reported to lead to enhanced CD14 expression, this could be a new susceptibility gene for rheumatoid arthritis (RA). We investigated whether this single nucleotide polymorphism (SNP) serves as a risk factor for disease development or...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
