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Article

The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs

1 Mar 2005

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Share to Reproductive Biology and Fertility
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Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 15759005
DOI: 10.1038/nature03362

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggsPMID 15759005Read ↗

Novel insights into the molecular mechanism of sperm–egg fusion via IZUMO1Semantic proximity Read ↗

Sperm-Egg InteractionSemantic proximity Read ↗

Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complexSemantic proximity Read ↗

Juno is the egg Izumo receptor and is essential for mammalian fertilizationSemantic proximity Read ↗

The Immunoglobulin-like Gene spe-45 Acts during Fertilization in Caenorhabditis elegans like the Mouse Izumo1 GeneSemantic proximity Read ↗

Sperm-Egg Fusion: A Molecular Enigma of Mammalian ReproductionSemantic proximity Read ↗

TMEM95 is a sperm membrane protein essential for mammalian fertilizationSemantic proximity Read ↗

Binding of sperm protein Izumo1 and its egg receptor Juno drives Cd9 accumulation in the intercellular contact area prior to fusion during mammalian fertilizationSemantic proximity Read ↗

A conserved fertilization complex bridges sperm and egg in vertebratesSemantic proximity Read ↗

The molecular players of sperm–egg fusion in mammalsSemantic proximity Read ↗

Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm−oocyte fusion in miceSemantic proximity Read ↗

Oocyte-triggered dimerization of sperm IZUMO1 promotes sperm–egg fusion in miceSemantic proximity Read ↗

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