Article
Atherogenic lipoprotein phenotype. A proposed genetic marker for coronary heart disease risk.
Circulation - 1 Aug 1990
Austin M A, King M C, Vranizan K M, Krauss R M
Abstract excerpt
In a community-based study of 301 subjects from 61 nuclear families, two distinct phenotypes (denoted A and B) were identified by nondenaturing gradient gel electrophoretic analysis of low density lipoprotein (LDL) subclasses. Phenotype A was characterized by predominance of large, buoyant LDL particles, and phenotype B consisted of a major peak of small, dense LDL particles. Previous analysis of the family data...
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