Atherogenic lipoprotein phenotype. A proposed genetic marker for coronary heart disease risk.

doi:10.1161/01.cir.82.2.495

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Article

Atherogenic lipoprotein phenotype. A proposed genetic marker for coronary heart disease risk.

Circulation - 1 Aug 1990

Austin M A, King M C, Vranizan K M, Krauss R M

Abstract excerpt

In a community-based study of 301 subjects from 61 nuclear families, two distinct phenotypes (denoted A and B) were identified by nondenaturing gradient gel electrophoretic analysis of low density lipoprotein (LDL) subclasses. Phenotype A was characterized by predominance of large, buoyant LDL particles, and phenotype B consisted of a major peak of small, dense LDL particles. Previous analysis of the family data...

Topics

Adolescent
Adult
Aged
Arteriosclerosis
Child
Child, Preschool
Cholesterol, HDL
Chromosome Mapping
Coronary Disease
Female
Genetic Markers
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lipids

Lipoproteins

Male

Middle Aged

Multivariate Analysis

Phenotype

Source

Open in PubMed

Identifiers

PMID: 2372896
DOI: 10.1161/01.cir.82.2.495

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2372896-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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