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Article

Audiological features and mitochondrial DNA sequence in a large family carrying mitochondrial A1555G mutation without use of aminoglycoside.

The Annals of otology, rhinology, and laryngology - 1 Feb 2005

Matsunaga Tatsuo, Kumanomido Hiroshi, Shiroma Masae, Goto Yu-ichi, Usami Shin-ichi

Abstract excerpt

To elucidate the pathophysiological and genetic mechanisms of hearing loss associated with the homoplasmic mitochondrial A1555G mutation in the absence of aminoglycoside exposure, we conducted audiological and genetic analyses on 67 maternally related members of a large Japanese family carrying this mutation. A consistent pattern was evident in the audiograms, with features of sensory presbycusis, cochlear origin...

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Source

Identifiers

PMID: 15757197
DOI: 10.1177/000348940511400213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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