Article
Sensorineural hearing loss caused by mitochondrial DNA mutations: special reference to the A1555G mutation.
Journal of communication disorders - 1 Jan 2000
Usami S, Abe S, Shinkawa H, Kimberling W J
Abstract excerpt
Mutations in mitochondrial DNA, which are maternally inherited, have been thought to be one of the causes of sensorineural hearing loss. Two mitochondrial mutational sites (A1555G, A7445G) have been reported to be responsible for non-syndromic hearing impairments. The A1555G mutation causes increased susceptibility to aminoglycoside antibiotic-induced hearing loss as well as non-syndromic sensorineural hearing...
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