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Article

Homocysteine levels--before and after methionine loading--in 51 Dutch families.

European journal of human genetics : EJHG - 1 Jun 2005

den Heijer Martin, Graafsma Sietze, Lee Soon Young, van Landeghem Bart, Kluijtmans Leo, Verhoef Petra, Beaty Terri H, Blom Henk

Abstract excerpt

Elevated levels of homocysteine are a risk factor for vascular disease, thrombosis, neural tube defects and dementia. The 677C>T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene appears to be the most important single determinant of plasma homocysteine concentration. In the current study, we estimated heritability and fit a series of models of inheritance for both fasting and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Source

Identifiers

PMID: 15756298
DOI: 10.1038/sj.ejhg.5201389

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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