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Article

Determinants of fasting and post-methionine homocysteine levels in families predisposed to hyperhomocysteinemia and premature vascular disease.

Arteriosclerosis, thrombosis, and vascular biology - 1 May 1999

de Jong S C, Stehouwer C D, van den Berg M, Kostense P J, Alders D, Jakobs C, Pals G, Rauwerda J A

Abstract excerpt

Elevated plasma total homocysteine (tHcy) levels, either measured in the fasting state or after oral methionine loading, are associated with an increased risk of atherothrombotic disease. Fasting and post-methionine hyperhomocysteinemia (HHC) overlap to a limited extent; both can occur as familial traits. We investigated determinants of fasting, postmethionine and delta (ie, post-methionine minus fasting levels)...

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PMID: 10323785
DOI: 10.1161/01.atv.19.5.1316

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MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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