Article
Identification of various MLL gene aberrations that lead to MLL gene mutation in patients with acute lymphoblastic leukemia (ALL) and infants with acute leukemia.
Leukemia research - 1 May 2005
Pais Anurita, Amare Kadam Pratibha, Raje Gauri, Sawant Manisha, Kabre Sharayu, Jain Hemani, Advani Suresh, Banavali Shripad
Abstract excerpt
Studies were done to investigate MLL gene aberrations using Conventional Cytogenetics, Southern blotting as well as FISH using a panel of probes on 218 cases which included 206 cases of pediatric/young adult ALL and 12 cases of infantile acute leukemias from Tata Memorial Hospital, India. The incidence of MLL gene rearrangements in acute lymphoblastic leukemia (ALL) was 9.4% which included infants as well as...
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