Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Missense mutations in the human insulin promoter factor-1 gene are not a common cause of type 2 diabetes mellitus in Taiwan.

Journal of endocrinological investigation - 1 Dec 2004

Shiau Ming-Yuh, Huang Chien-Ning, Liao Jung-Hua, Chang Yih-Hsin

Abstract excerpt

Type 2 diabetes mellitus (T2DM) is a common metabolic disorder characterized by a hyperglycemia resulting from defect in insulin secretion and insulin action. Recent studies showed that dominant negative mutations in the insulin promoter factor-1 (IPF-1), a pancreatic beta-cell specific transcription factor, cause maturity-onset diabetes of the young (MODY), a subtype of T2DM with early onset and monogenic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Homeodomain Proteins

Share to Mutation, Missense

Share to Polymorphism, Restriction Fragment Length

Share to Taiwan

Share to Trans-Activators

Source

Identifiers

PMID: 15754742
DOI: 10.1007/BF03345313

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Missense mutations in the human insulin promoter factor-1 gene are not a common cause of type 2 diabetes mellitus in Taiwan.PMID 15754742Read ↗

Mutations in the coding region of the insulin promoter factor 1 gene are not a common cause of maturity-onset diabetes of the young in Japanese subjects.Semantic proximity Read ↗

Missense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetes.Semantic proximity Read ↗

Insulin promoter factor-1 mutations and diabetes in Trinidad: identification of a novel diabetes-associated mutation (E224K) in an Indo-Trinidadian family.Semantic proximity Read ↗

Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus.Semantic proximity Read ↗

[The genetic and clinical characteristics of transcription factor 1 gene mutations in Chinese diabetes].Semantic proximity Read ↗

Identification of a single nucleotide insertion polymorphism in the upstream region of the insulin promoter factor-1 gene: an association study with diabetes mellitus.Semantic proximity Read ↗

No association between polymorphisms in the INSIG1 gene and the risk of type 2 diabetes and related traits.Semantic proximity Read ↗

A newly identified mutation in an IPF1 binding site of the insulin gene promoter may predispose to type 2 diabetes mellitus.Semantic proximity Read ↗

IPF-1/MODY4 gene missense mutation in an Italian family with type 2 and gestational diabetes.Semantic proximity Read ↗

Insulin Promoter Factor 1 variation is associated with type 2 diabetes in African Americans.Semantic proximity Read ↗

Functional consequences of mutations in the MODY4 gene (IPF1) and coexistence with MODY3 mutations.Semantic proximity Read ↗

Common polymorphisms of the PAI1 gene do not play a major role in the development of diabetic nephropathy in Type 1 diabetes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.