Article
Association of a haplotype block spanning SDAD1 gene and CXC chemokine genes with allergic rhinitis.
The Journal of allergy and clinical immunology - 1 Mar 2005
Zhang Jian, Noguchi Emiko, Migita Ohsuke, Yokouchi Yukako, Nakayama Junko, Shibasaki Masanao, Arinami Tadao
Abstract excerpt
BACKGROUND: Seasonal allergic rhinitis (SAR) is a common allergic disorder characterized by episodes of sneezing, rhinorrhea, and swelling of the nasal mucosa. Although the pathogenesis of SAR remains unclear, there does appear to be a genetic predisposition to development of SAR. We previously identified regions of chromosomes 1p, 4q, and 9q linked to SAR in 48 families (188 members) identified through children...
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