Article
Association of ADAM33 gene polymorphisms with adult allergic asthma and rhinitis in a Chinese Han population.
BMC medical genetics - 9 Sept 2008
Su Dongju, Zhang Ximei, Sui Hong, Lü Fuzhen, Jin Lianhong, Zhang Jing
Abstract excerpt
BACKGROUND: Rhinitis and asthma are very common diseases involving genetic and environmental factors. Most patients with asthma also have rhinitis, which suggests the concept of 'one airway, one disease.' A disintegrin and metalloproteinase 33 (ADAM33) is the first asthma-susceptible gene to be discovered by positional cloning. To evaluate the potential influence of ADAM33 gene polymorphisms on allergic rhinitis...
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