Article
A haplotype in the inducible T-cell tyrosine kinase is a risk factor for seasonal allergic rhinitis.
Allergy - 1 Sept 2009
Benson M, Mobini R, Barrenäs F, Halldén C, Naluai A T, Säll T, Cardell L O
Abstract excerpt
BACKGROUND: Identification of disease-associated single nucleotide polymorphisms (SNPs) in seasonal allergic rhinitis (SAR) may be facilitated by focusing on genes in a disease-associated pathway. OBJECTIVE: To search for SNPs in genes that belong to the T-cell receptor (TCR) pathway and that change in expression in allergen-challenged CD4+ cells from patients with SAR. METHODS: CD4+ cells from patients with SAR...
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