Article
Association of ADAM33 gene polymorphisms with adult concomitant allergic rhinitis and asthma in Chinese Han population.
Molecular biology reports - 1 Jul 2009
Zhang Ximei, Su Dongju, Zhang Xuelong, Sui Hong, Jin Lianhong, Lü Fuzhen, Zhang Jing
Abstract excerpt
Allergic Rhinitis (AR) and allergic asthma (AS) are very common diseases involving genetic and environmental factors. Most patients with asthma also have rhinitis, which suggests the concept of 'one airway, one disease'. A disintegrin and metalloproteinase 33 (ADAM33) was discovered as the first asthma-susceptible gene by positional cloning. To evaluate the potential influences of ADAM33 gene polymorphisms on...
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